Jervine | Tocris Bioscience 4717/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Jervine

catalog :

4717/10

quantity :

10 mg

price :

165 USD

product information

brand :

Tocris

MasterCode :

4717

SKU :

4717/10

product name :

Jervine

unit sizes :

10 mg

description :

Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo

target :

Hedgehog Signaling Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

425.6

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Jervine is an inhibitor of Hedgehog signaling (IC50 = 500 - 700 nM); binds directly to Smoothened (Smo). Inhibits the response of target tissues to Sonic hedgehog signaling, possibly via the sterol sensing domain of Patched. Teratogenic.

extended description :

Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo

chemical name text :

(2 R,3S,3 R,3 aS,6 S,6aS,6bS,7 aR,11aS,11bR)-2,3,3 a,4,4 ,5 ,6,6 ,6a,6b,7,7 ,7 a,8,11a,11b-hexadecahydro-3-hydroxy-3 ,6 ,10,11b-tetramethyl-Spiro[9H-benzo[a]fluorene-9,2 (3 H)-furo

formula :

C 27 H 39 NO 3

formula text :

C27H39NO3

cas num :

469-59-0

USD :

165 USD

product details :

Inhibitor of Hedgehog (Hh) signaling; binds directly to Smo

storage :

Store at -20°C