Salmeterol xinafoate | Tocris Bioscience 4712 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Salmeterol xinafoate

catalog :

4712

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Pon C, Lane J, Sloan E, Halls M. The Î²2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion. FASEB J. 2016;30:1144-54 pubmed publisher
IsraÃ«l Assayag E, Beaulieu M, Cormier Y. ASM-024, a piperazinium compound, promotes the in vitro relaxation of Î²2-adrenoreceptor desensitized tracheas. PLoS ONE. 2015;10:e0120095 pubmed publisher
Zaytseva N, Lynn J, Wu Q, Mudaliar D, Sun H, Kuang P, et al. Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens Actuators B Chem. 2013;188: pubmed publisher
Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth S, Kreutz M, et al. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via ?-adrenergic signaling in thalamocortical relay neurons. PLoS ONE. 2011;6:e27474 pubmed publisher
Sykes D, Charlton S. Slow receptor dissociation is not a key factor in the duration of action of inhaled long-acting ?2-adrenoceptor agonists. Br J Pharmacol. 2012;165:2672-83 pubmed publisher
Scola A, Loxham M, Charlton S, Peachell P. The long-acting beta-adrenoceptor agonist, indacaterol, inhibits IgE-dependent responses of human lung mast cells. Br J Pharmacol. 2009;158:267-76 pubmed publisher
Nackley A, Tan K, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both beta2- and beta3-adrenergic receptors. Pain. 2007;128:199-208 pubmed

product information

brand :

Tocris

master code :

4712

SKU :

4712/10

product name :

Salmeterol xinafoate

description :

Long-acting 2 agonist; bronchodilator

target :

Adrenergic beta-2 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

603.75

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Long-acting 2 adrenergic receptor agonist. Inhibits the release of histamine, leukotrienes and prostaglandin D2, and blocks GM-CSF production from human cultured mast cells. Exhibits efficacious bronchodilatory activity in patients with asthma or chronic obstructive pulmonary disease (COPD).

catalog number base :

4712

product keywords :

long acting beta2 b2 2 adrenergics adrenoceptors agonists LABAs asthma COPD respiratory disease bronchodilators Adrenergic Beta-2 Receptors 4712,

extended description :

Long-acting 2 agonist; bronchodilator

chemical name text :

4-Hydroxy- 1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthalenecarboxylic acid salt

formula :

C 25 H 37 NO 4 .C 11 H 8 O 3

formula text :

C25H37NO4.C11H8O3

cas num :

94749-08-3

2020 USD :

145

2021 USD :

151 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage