TC LPA5 4 | Tocris Bioscience 4708/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TC LPA5 4

catalog :

4708/10

quantity :

10 mg (also 50 mg)

price :

270 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Plastira I, Bernhart E, Goeritzer M, DeVaney T, Reicher H, Hammer A, et al. Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype. J Neuroinflammation. 2017;14:253 pubmed publisher
Kittaka H, Uchida K, Fukuta N, Tominaga M. Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1. J Physiol. 2017;595:2681-2698 pubmed publisher

product information

brand :

Tocris

master code :

4708

SKU :

4708/10

rank :

0.061

product name :

TC LPA5 4

description :

LPA5 receptor antagonist

target :

Lysophosphatidic Acid (LPA) Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC LPA5 4 is an LPA5 receptor antagonist (IC50 = 0.8 M in LPA5-RH7777 cells). TC LPA5 4 inhibits LPA-induced aggregation of isolated human platelets. Exhibits selectivity for LPA5 against 80 other screened targets.

extended description :

LPA5 receptor antagonist

chemical name text :

5-(3-Chloro-4-cyclohexylphenyl)-1-(3-methoxyphenyl)-1H-pyrazole-3-carboxylic acid

formula :

C 23 H 23 ClN 2 O 3

formula text :

C23H23ClN2O3

cas num :

1393814-38-4

USD :

270 USD

product details :

LPA5 receptor antagonist

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage