Borrelidin | Tocris Bioscience 4706/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Borrelidin

catalog :

4706/1

quantity :

1 mg

price :

392 USD

product information

brand :

Tocris

MasterCode :

4706

SKU :

4706/1

product name :

Borrelidin

target :

Synthase/Synthetase Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

489.64

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Borrelidin is an antibiotic and antiangiogenic. Selectively inhibits threonyl-tRNA synthetase (ThrRS). Exhibits antiangiogenic activity in a mouse model of tumor angiogenesis. Induces apoptosis in capillary tube-forming endothelial cells; disrupts capillary tubes and inhibits their formation (IC50 = 0.8 nM in rat aorta). Induces the unfolded protein response (UPR) and apoptosis in oral cancer cells.

extended description :

Antiangiogenic; inhibits threonyl-tRNA synthetase

chemical name text :

(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid

formula :

C 28 H 43 NO 6

formula text :

C28H43NO6

cas num :

7184-60-3

USD :

392 USD

product details :

Antiangiogenic; inhibits threonyl-tRNA synthetase

storage :

Store at -20°C