Chetomin | Tocris Bioscience 4705 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Chetomin

catalog :

4705

quantity :

1 mg

price :

212 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Mousavizadeh R, Scott A, LU A, Ardekani G, Behzad H, Lundgreen K, et al. Angiopoietin-like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblasts. J Physiol. 2016;594:2971-83 pubmed publisher

product information

brand :

Tocris

master code :

4705

SKU :

4705/1

product name :

Chetomin

description :

Blocks interaction of HIF-1 , HIF-2 and STAT2 with CBP/p300

target :

HIF Inhibitors

category :

Small Molecules

unit size :

1 mg

purity :

98%

observed molecular weight :

710.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Targets the CH1 domain of CBP/p300; inhibits interaction of HIF-1 , HIF-2 and STAT2 with CBP/p300. Attenuates hypoxia-induced gene expression in vitro and in vivo ; radiosensitizes human HT 1080 fibrosarcoma cells in vitro .

catalog number base :

4705

product keywords :

NSC289491 p300/CBP disrupts interaction HIF1a HIF2a STAT2 hypoxia inducible factors hypoxic gene expression Hypoxia Inducible Factors 4705, Hypoxia Inducible Factors, Hypoxia Inducible Factor

extended description :

Blocks interaction of HIF-1 , HIF-2 and STAT2 with CBP/p300

chemical name text :

(3S,5aR,10bS,11aS)-2,3,5a,6,10b,11-hexahydro-3-(hydroxymethyl)-10b-(3-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl)methyl]-1H-indol-1-yl]-2-methyl-3,11a-epidithio-11aH-pyrazino[1 ,2 :1,5]pyrrolo[

formula :

C 31 H 30 N 6 O 6 S 4

formula text :

C31H30N6O6S4

cas num :

1403-36-7

2020 USD :

205

2021 USD :

212 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage