ETP 45658 | Tocris Bioscience 4702 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ETP 45658

catalog :

4702

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Maswadeh H, Aljarbou A, Alorainy M, Rahmani A, Khan M. Coadministration of doxorubicin and etoposide loaded in camel milk phospholipids liposomes showed increased antitumor activity in a murine model. Int J Nanomedicine. 2015;10:2847-55 pubmed publisher

product information

brand :

Tocris

master code :

4702

SKU :

4702/10

product name :

ETP 45658

description :

Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR

target :

PI 3-Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

311.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-K , PI 3-K , PI 3-K and PI 3-K respectively). Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively). Inhibits proliferation of multiple cancer cell lines in vitro and reduces Akt phosphorylation levels in vivo .

catalog number base :

4702

product keywords :

ETP45658 PI3-K kinases inhibitors kinases inhibits dna-pk mtor PI3Ka PI3Kalpha PI3Kd PI3Kdelta PI3Kb PI3Kbeta PI3Kg PI3Kgamma PI3K PI3K PI3K PI3K PI 3-Kinase mTOR DNA-dependent Protein Kinase 4702,

extended description :

Potent PI 3-kinase inhibitor; also inhibits DNA-PK and mTOR

chemical name text :

3-[1-Methyl-4-(4-morpholinyl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylphenol

formula :

C 16 H 17 N 5 O 2

cas num :

1198357-79-7

2020 USD :

205

2021 USD :

205 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage