NAV 26 | Tocris Bioscience 4691/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NAV 26

catalog :

4691/10

quantity :

10 mg (also 50 mg)

price :

238 USD

citations: 1

Reference
Shen H, Li L, Yang S, Wang D, Zhou S, Chen X, et al. Regulatory role of tumor necrosis factor receptor-associated factor 6 in breast cancer by activating the protein kinase B/glycogen synthase kinase 3β signaling pathway. Mol Med Rep. 2017;16:2269-2273 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4691

SKU :

4691/10

product name :

NAV 26

Description :

Selective Nav1.7 channel blocker

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

434.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NAV 26 is a selective Nav1.7 channel blocker (IC50 = 370 nM). Exhibits 85-fold selectivity for Nav1.7 over Nav1.5 and hERG channels. Reduces nociceptive behavior in rat models of pain.

extended description :

Selective Nav1.7 channel blocker

chemical name text :

2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide

formula :

C 22 H 21 F 3 N 2 O 4

formula text :

C22H21F3N2O4

cas num :

1198160-14-3

USD :

238 USD

product details :

Selective Nav1.7 channel blocker

storage :

Store at +4°C