Xanthohumol | Tocris Bioscience 4686/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Xanthohumol

catalog :

4686/10

quantity :

10 mg

price :

234 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
den Brok M, Bull C, Wassink M, de Graaf A, Wagenaars J, Minderman M, et al. Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation. Nat Commun. 2016;7:13324 pubmed publisher

product information

brand :

Tocris

master code :

4686

SKU :

4686/10

rank :

0.061

product name :

Xanthohumol

description :

p97 ATPase (VCP) inhibitor

target :

Other ER Stress/UPR Inhibitors

category :

Small Molecules

sizes available :

10 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Xanthohumol is a p97 ATPase (VCP) inhibitor. Binds to the N domain of p97, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC50 = 50.3 M).

extended description :

p97 ATPase (VCP) inhibitor

chemical name text :

(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one

formula :

C 21 H 22 O 5

formula text :

C21H22O5

cas num :

6754-58-1

USD :

234 USD

product details :

p97 ATPase (VCP) inhibitor

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage