product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
KL 001
catalog :
4685
quantity :
10 mg (also 50 mg)
price :
189 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
4685
SKU :
4685/10
product name :
KL 001
description :
Cryptochrome protein stabilizer; lengthens circadian period
target :
Additional Transcription Factor Compounds
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
398.48
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cryptochrome protein (CRY) stabilizer; blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 fibroblasts without altering casein kinase activity. Represses glucagon-induced hepatic gluconeogenesis through the induction of Pck1 and G6pc expression.
catalog number base :
4685
product keywords :
KL001 cryptochrome stabilizers CRY CRY1 CRY2 circadian clock rhythms gluconeogenesis regulator Other Transcription Factors 4685,
extended description :
Cryptochrome protein stabilizer; lengthens circadian period
chemical name text :
N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide
formula :
C 21 H 22 N 2 O 4 S
formula text :
C21H22N2O4S
cas num :
309928-48-1
2020 USD :
183
2021 USD :
189 USD
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK