This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
CCT 031374 hydrobromide
catalog :
4675/10
quantity :
10 mg (also 50 mg)
price :
219 USD
citations: 2
Reference
Brown B, Connolly G, Mill C, Williams H, Angelini G, Johnson J, et al. Aging differentially modulates the Wnt pro-survival signalling pathways in vascular smooth muscle cells. Aging Cell. 2018;:e12844 pubmed publisher
Liu B, Wu S, Han L, Zhang C. β-catenin signaling induces the osteoblastogenic differentiation of human pre-osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression. Int J Mol Med. 2015;36:1572-82 pubmed publisher
product information
brand :
Tocris
master code :
4675
SKU :
4675/10
product name :
CCT 031374 hydrobromide
description :
Inhibits TCF-dependent transcription; lowers -catenin levels
target :
beta-Catenin Inhibitors
category :
Small Molecules
unit sizes :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
434.33
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
CCT 031374 hydrobromide is an inhibitor of TCF-dependent transcription. Blocks BIO -induced -catenin stabilization; reduces nuclear and cytosolic -catenin levels in mouse L-cells. Inhibits growth and reduces TCF-dependent transcription in SW480 colon carcinoma cells.
extended description :
Inhibits TCF-dependent transcription; lowers -catenin levels
chemical name text :
1-[1,1 -Biphenyl]-4-yl-2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)ethanone hydrobromide
formula :
C 23 H 19 N 3 O.HBr
formula text :
C23H19N3O.HBr
cas num :
1219184-91-4
USD :
219 USD
product details :
Inhibits TCF-dependent transcription; lowers -catenin levels
storage :
Desiccate at RT
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK