SB 223412 | Tocris Bioscience 4672/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 223412

catalog :

4672/10

quantity :

10 mg (also 50 mg)

price :

214 USD

product information

brand :

Tocris

master code :

4672

SKU :

4672/10

product name :

SB 223412

target :

NK3 Receptor Antagonists

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

382.45

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 223412 is a potent and selective non-peptide NK3 receptor antagonist (Ki values are 1, 144 and 100000 nM for human NK3, NK2 and NK1 receptors respectively). Selective over a panel of 60 receptors, enzymes and ion channels at concentrations of 1 or 10 M. Inhibits NKB-induced Ca2+ mobilization in vitro (IC50 = 16.6 nM) and inhibits NK3-agonist-induced behavioral responses in vivo . Orally active and brain penetrant.

extended description :

Potent, selective non-peptide NK3 antagonist. Brain penetrant

chemical name text :

3-Hydroxy-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide

formula :

C 25 H 22 N 2 O 2

cas num :

174636-32-9

USD :

214 USD

product details :

Potent, selective non-peptide NK3 antagonist. Brain penetrant

storage :

Store at +4°C