chemical

SB 706375

4667

10 mg (also 50 mg)

185 USD

4667

4667/10

SB 706375

High affinity, non-peptide UT receptor antagonist

Urotensin-II Receptor Antagonists

Small Molecules

10 mg (also 50 mg)

98%

539.36

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

High affinity, non-peptide antagonist of the urotensin-II (UT) receptor. Exhibits high affinity for mammalian UT receptors, including human, mouse and rat (Ki values are 9.3, 19.1 and 20.7 nM respectively, in HEK293 cells expressing recombinant UT receptors). Also inhibits binding of radiolabeled urotensin to endogenous human UT receptors (Ki = 5.4 nM in a whole-cell binding assay). Displays 100-fold selectivity for the human UT receptor over 86 different receptors, ion channels, enzymes, transporters and nuclear hormones.

4667

SB706375 urotensin-II U-II receptors UT antagonists high affinity Urotensin-II Receptors 4667,

High affinity, non-peptide UT receptor antagonist

2-Bromo-4,5-dimethoxy-N-[3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]-4-(trifluoromethyl)phenyl]benzenesulfonamide

C 20 H 22 BrF 3 N 2 O 5 S

C20H22BrF3N2O5S

733734-61-7

185

185 USD

Store at RT