Obtustatin | Tocris Bioscience 4664 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Obtustatin

catalog :

4664

quantity :

100 ug

price :

331 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Baghdadi M, Castel D, Machado L, Fukada S, Birk D, Relaix F, et al. Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche. Nature. 2018;557:714-718 pubmed publisher
Mogami H, Kishore A, Word R. Collagen Type 1 Accelerates Healing of Ruptured Fetal Membranes. Sci Rep. 2018;8:696 pubmed publisher

product information

brand :

Tocris

master code :

4664

SKU :

4664/100U

product name :

Obtustatin

description :

Potent and selective 1 1 inhibitor

target :

Integrin Receptor Inhibitors

category :

Peptides

unit size :

100 ug

observed molecular weight :

4393.07

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Highly potent integrin 1 1 inhibitor (IC50 = 0.8 nM for 1 1 binding to type IV collagen). Selective for 1 1 over 2 1, IIb 3, v 3, 4 1, 5 6, 9 1 and 4 7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma; blocks human melanoma growth in nude mice.

catalog number base :

4664

product keywords :

integrins alpha1beta1 a1b1 a n potent selective inhibitors inhibits antiangiogenics angiogenesis Integrins Cell Adhesion Molecules Antiangiogenics 4664,

extended description :

Potent and selective 1 1 inhibitor

formula :

C 184 H 284 N 52 O 57 S 8

formula text :

C184H284N52O57S8

2020 USD :

318

2021 USD :

331 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage