KB SRC 4 | Tocris Bioscience 4660/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KB SRC 4

catalog :

4660/10

quantity :

10 mg (also 50 mg)

price :

345 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Carmona G, Perera U, Gillett C, Naba A, Law A, Sharma V, et al. Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE. Oncogene. 2016;35:5155-69 pubmed publisher
Kim Y, Park K, Kim J, Seo H, Shin K, Lee Y, et al. An endoplasmic reticulum stress-initiated sphingolipid metabolite, ceramide-1-phosphate, regulates epithelial innate immunity by stimulating β-defensin production. Mol Cell Biol. 2014;34:4368-78 pubmed publisher

product information

brand :

Tocris

master code :

4660

SKU :

4660/10

rank :

0.061

product name :

KB SRC 4

description :

Potent and selective c-Src inhibitor

target :

Src Family Kinase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

KB SRC 4 is a potent and selective c-Src inhibitor (Ki = 44 nM); does not inhibit c-Abl at concentrations up to 125 M. Selective between Src family members (Kd values are 86, 160, 240, 720, 3200, 4400, and >40,000 nM for c-Src, Lck, Fgr, Yes, Lyn, Hck and Fyn respectively). Significantly inhibits cell growth in 4T1 mammary carcinoma tumor cells.

extended description :

Potent and selective c-Src inhibitor

chemical name text :

1-[3-[1-([1,1 -Biphenyl]-3-ylmethyl)-1H-1,2,3-triazol-5-yl]phenyl]-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

formula :

C 32 H 23 ClN 8

formula text :

C32H23ClN8

cas num :

1380088-03-8

USD :

345 USD

product details :

Potent and selective c-Src inhibitor

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage