Zolmitriptan | Tocris Bioscience 4657 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Zolmitriptan

catalog :

4657

quantity :

10 mg (also 50 mg)

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed publisher

product information

brand :

Tocris

master code :

4657

SKU :

4657/10

product name :

Zolmitriptan

description :

Potent 5-HT1B/1D/1F agonist

target :

5-HT1D Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

287.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent 5-HT1B/1D/1F agonist (Ki values are 0.63, 5.01 and 63.09 nM for h5-HT1D, h5-HT1B and h5-HT1F receptors respectively). Inhibits trigeminal nerve stimulation-mediated neurogenic plasma protein extravasation in guinea pigs; blocks long excitatory postsynaptic potentials (EPSPs) in a rat model of spinal cord injury.

catalog number base :

4657

product keywords :

5ht 5-ht serotonergics 5ht1B 5ht1D 5ht1F potent agonists excitatory postsynaptic potentials migraine neurogenic plasma protein extravasation 5-HT1B Receptors 5-HT1D Receptors 5-HT1F Receptors 4657,

extended description :

Potent 5-HT1B/1D/1F agonist

chemical name text :

(4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone

formula :

C 16 H 21 N 3 O 2

formula text :

C16H21N3O2

cas num :

139264-17-8

2020 USD :

2021 USD :

86 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage