NSC 74859 | Tocris Bioscience 4655/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 74859

catalog :

4655/10

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4655

SKU :

4655/10

rank :

0.061

product name :

NSC 74859

description :

Selective STAT3 inhibitor

target :

STAT Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NSC 74859 selectively inhibits STAT3 DNA-binding activity in vitro (IC50 values are 86, 160, and >300 M for STAT3-STAT3, STAT1-STAT3 and STAT1-STAT1 DNA-binding activity respectively). NSC 74859 blocks growth and induces apoptosis preferentially in tumor cells that contain persistently active STAT3 in vitro and arrests tumor growth in a murine xenograft model in vivo .

extended description :

Selective STAT3 inhibitor

chemical name text :

2-Hydroxy-4-[[2-[[(4-methylphenyl)sulfonyl]oxy]acetyl]amino]benzoic acid

formula :

C 16 H 15 NO 7 S

formula text :

C16H15NO7S

cas num :

501919-59-1

USD :

201 USD

product details :

Selective STAT3 inhibitor

alt names :

S3I-201

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage