SAHA | Tocris Bioscience 4652/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SAHA

catalog :

4652/10

quantity :

10 mg (also 50 mg)

price :

89 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Ng Blichfeldt J, Schrik A, Kortekaas R, Noordhoek J, Heijink I, Hiemstra P, et al. Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation. EBioMedicine. 2018;36:461-474 pubmed publisher
Bhattacharya S, Srinivasan K, Abdisalaam S, Su F, Raj P, Dozmorov I, et al. RAD51 interconnects between DNA replication, DNA repair and immunity. Nucleic Acids Res. 2017;45:4590-4605 pubmed publisher
Sarenac T, Trapecar M, Gradisnik L, Rupnik M, Pahor D. Single-cell analysis reveals IGF-1 potentiation of inhibition of the TGF-?/Smad pathway of fibrosis in human keratocytes in vitro. Sci Rep. 2016;6:34373 pubmed publisher

product information

brand :

Tocris

master code :

4652

SKU :

4652/10

rank :

0.061

product name :

SAHA

description :

Class I and II HDAC inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro . Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.

extended description :

Class I and II HDAC inhibitor

chemical name text :

N-Hydroxy-N -phenyloctanediamide

formula :

C 14 H 20 N 2 O 3

formula text :

C14H20N2O3

cas num :

149647-78-9

USD :

89 USD

product details :

Class I and II HDAC inhibitor

alt names :

Vorinostat

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage