PCI 34051 | Tocris Bioscience 4643 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PCI 34051

catalog :

4643

quantity :

10 mg (also 50 mg)

price :

116 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Kim D, Dunleavey J, Xiao L, Ollila D, Troester M, Otey C, et al. Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition. Br J Cancer. 2018;118:1359-1368 pubmed publisher

product information

brand :

Tocris

master code :

4643

SKU :

4643/10

product name :

PCI 34051

description :

Potent and selective HDAC8 inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

296.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays 200 fold selectivity over HDAC isoforms 1, 2, 3, 6 and 10. Induces apoptosis in cell lines derived from T cell lymphomas or leukemias.

catalog number base :

4643

product keywords :

PCI34051 potent selective histone deacetylase 8 (HDAC8) inhibitors inhibits epigenetics Apoptosis Inducers Class I HDACs 4643,

extended description :

Potent and selective HDAC8 inhibitor

chemical name text :

N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide

formula :

C 17 H 16 N 2 O 3

formula text :

C17H16N2O3

cas num :

950762-95-5

2020 USD :

144

2021 USD :

116 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage