product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
PCI 34051
catalog :
4643/10
quantity :
10 mg (also 50 mg)
price :
147 USD
more info or order :
Tocris Bioscience product webpage
citations: 1
Reference
Kim D, Dunleavey J, Xiao L, Ollila D, Troester M, Otey C, et al. Suppression of TGFβ-mediated conversion of endothelial cells and fibroblasts into cancer associated (myo)fibroblasts via HDAC inhibition. Br J Cancer. 2018;118:1359-1368 pubmed publisher
product information
brand :
Tocris
catalog number base :
4643
SKU :
4643/10
product name :
PCI 34051
units size :
10 mg (also 50 mg)
description :
Potent and selective HDAC8 inhibitor
target :
Class I Histone Deacetylases Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
296.32
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
review stars :
5
details of functionality :
PCI 34051 is a potent and selective histone deacetylase 8 (HDAC8) inhibitor (IC50 = 10 nM). Displays 200 fold selectivity over HDAC isoforms 1, 2, 3, 6 and 10. Induces apoptosis in cell lines derived from T cell lymphomas or leukemias.
top caption :
Potent and selective HDAC8 inhibitor
extended description :
Potent and selective HDAC8 inhibitor
chemical name text :
N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide
formula :
C17H16N2O3
formula text :
C17H16N2O3
cas num :
950762-95-5
USD :
147 USD
product details :
Potent and selective HDAC8 inhibitor
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK