SC 79 | Tocris Bioscience 4635 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SC 79

catalog :

4635

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Wang L, Chen Y, Guan C, Zhao Z, Li Q, Yang J, et al. Using low-risk factors to generate non-integrated human induced pluripotent stem cells from urine-derived cells. Stem Cell Res Ther. 2017;8:245 pubmed publisher
Wilson N, Olm Shipman A, Acevedo D, Palaniyandi K, Hall E, Kosa E, et al. SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination. Sci Rep. 2016;6:17735 pubmed publisher
Sladitschek H, Neveu P. The bimodally expressed microRNA miR-142 gates exit from pluripotency. Mol Syst Biol. 2015;11:850 pubmed publisher
Bei Y, Song Y, Wang F, Dimitrova Shumkovska J, Xiang Y, Zhao Y, et al. miR-382 targeting PTEN-Akt axis promotes liver regeneration. Oncotarget. 2016;7:1584-97 pubmed publisher
Moreira J, Wohlwend M, Alves M, WislÃ¸ff U, Bye A. A small molecule activator of AKT does not reduce ischemic injury of the rat heart. J Transl Med. 2015;13:76 pubmed publisher

product information

brand :

Tocris

master code :

4635

SKU :

4635/10

product name :

SC 79

description :

Akt activator

target :

Akt (Protein Kinase B) Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

364.78

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Activator of Akt; binds to the pleckstrin homology domain of Akt. Enhances Akt phosphorylation by upstream protein kinases; also enables cytosolic activation of Akt. Shown to suppress excitotoxicity-induced neuronal death in vitro and in vivo . Exhibits brain penetrance.

catalog number base :

4635

product keywords :

SC79 Akt protein kinase B PKB activators activates brain penetrant Akt (Protein Kinase B) Protein Kinase B/Akt 4635,

extended description :

Akt activator

chemical name text :

2-Amino-6-chloro- -cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester

formula :

C 17 H 17 ClN 2 O 5

formula text :

C17H17ClN2O5

cas num :

305834-79-1

2020 USD :

187

2021 USD :

195 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage