product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
4633/1
catalog :
4633/1
quantity :
1 mg
price :
239 USD
more info or order :
citations: 6
Reference
Fernández Duran I, Quintanilla A, Tarrats N, Birch J, Hari P, Millar F, et al. Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence. Cell Death Differ. 2022;29:1267-1282 pubmed publisher
Martin E, Pacholewska A, Patel H, Dashora H, Sung M. Integrative analysis suggests cell type-specific decoding of NF-κB dynamics. Sci Signal. 2020;13: pubmed publisher
Ishisono K, Mano T, Yabe T, Kitaguchi K. Dietary Fiber Pectin Ameliorates Experimental Colitis in a Neutral Sugar Side Chain-Dependent Manner. Front Immunol. 2019;10:2979 pubmed publisher
Inoue M, Niki M, Ozeki Y, Nagi S, Chadeka E, Yamaguchi T, et al. High-density lipoprotein suppresses tumor necrosis factor alpha production by mycobacteria-infected human macrophages. Sci Rep. 2018;8:6736 pubmed publisher
Bi J, Koivisto L, Pang A, Li M, Jiang G, Aurora S, et al. Suppression of αvβ6 Integrin Expression by Polymicrobial Oral Biofilms in Gingival Epithelial Cells. Sci Rep. 2017;7:4411 pubmed publisher
Murphy K, Whitehead J, Falahee P, Zhou D, Simon S, Leach J. Multifactorial Experimental Design to Optimize the Anti-Inflammatory and Proangiogenic Potential of Mesenchymal Stem Cell Spheroids. Stem Cells. 2017;35:1493-1504 pubmed publisher
image
image 1 :
Tocris Bioscience 4633/1 image 1
Cat.No. 4633 - Pam3CSK4 Pam-Cys(Pam2)-Ser-Lys-Lys-Lys-Lys (Cys(Pam2) = S-[2,3-Bis(palmitoyloxy)-(2-R/S)-propyl]-Cys) CAS No. 112208-00-1
product information
master code :
4633
SKU :
4633/1
product name :
Pam3CSK4
unit size :
1 mg
description :
TLR1/2 agonist; induces cytokine production
target :
Toll-like Receptor Agonists
category :
Peptides
purity :
95%
observed molecular weight :
1510.24
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist; induces production of TNF- and IL-6 in macrophages. Stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells. Promotes differentiation of naive CD4+ T cells into Th17 cells.
top caption :
TLR1/2 agonist; induces cytokine production
extended description :
TLR1/2 agonist; induces cytokine production
formula :
C81H156N10O13S
formula text :
C81H156N10O13S
cas num :
112208-00-1
USD :
239 USD
product details :
TLR1/2 agonist; induces cytokine production
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK