Melphalan | Tocris Bioscience 4619/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Melphalan

catalog :

4619/50

quantity :

50 mg

price :

118 USD

citations: 2

Reference
Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed publisher
Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;: pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4619

SKU :

4619/50

product name :

Melphalan

Description :

DNA alkylating agent; cytotoxic and antineoplastic

target :

Additional Apoptosis-related Compounds

category :

Small Molecules

unit size :

50 mg

purity :

95%

observed molecular weight :

305.2

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Melphalan is a DNA alkylating agent; induces cytotoxicity through the formation of stable interstrand and intrastrand crosslinks within DNA. Inhibits growth of PC-3 cells (IC50 values are 0.074 and 0.77 g/ml for sequential dosing and single dosing respectively).

extended description :

DNA alkylating agent; cytotoxic and antineoplastic

chemical name text :

4-[Bis(2-Chloroethyl)amino]-L-phenylalanine

formula :

C 13 H 18 Cl 2 N 2 O 2

formula text :

C13H18Cl2N2O2

cas num :

148-82-3

USD :

118 USD

product details :

DNA alkylating agent; cytotoxic and antineoplastic

storage :

Store at RT