4612/10 | Tocris Bioscience 4612/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4612/10

catalog :

4612/10

quantity :

10 mg (also 50 mg)

price :

209 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Davatolhagh M, Fuccillo M. Neurexin1⍺ differentially regulates synaptic efficacy within striatal circuits. Cell Rep. 2021;34:108773 pubmed publisher
Morena M, Leitl K, Vecchiarelli H, Gray J, Campolongo P, Hill M. Emotional arousal state influences the ability of amygdalar endocannabinoid signaling to modulate anxiety. Neuropharmacology. 2016;111:59-69 pubmed publisher
Vilela L, Gomides L, David B, Antunes M, Diniz A, Moreira F, et al. Cannabidiol rescues acute hepatic toxicity and seizure induced by cocaine. Mediators Inflamm. 2015;2015:523418 pubmed publisher
Sardinha J, Kelly M, Zhou J, Lehmann C. Experimental cannabinoid 2 receptor-mediated immune modulation in sepsis. Mediators Inflamm. 2014;2014:978678 pubmed publisher
Butti E, Bacigaluppi M, Rossi S, Cambiaghi M, Bari M, Cebrian Silla A, et al. Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity. Brain. 2012;135:3320-35 pubmed publisher
Hamtiaux L, Masquelier J, Muccioli G, Bouzin C, Feron O, Gallez B, et al. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action. BMC Cancer. 2012;12:92 pubmed publisher

product information

master code :

4612

SKU :

4612/10

product name :

URB 597

unit size :

10 mg (also 50 mg)

description :

Potent and selective FAAH inhibitor

target :

Fatty Acid Amide Hydrolase (FAAH) Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

338.4

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

URB 597 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor (IC50 values are 3 and 5 nM in human liver and rat brain, respectively). Exhibits no significant inhibitory activity against a variety of receptors, ion channels and enzymes, including human cannabinoid receptors and rat monoacylglycerol lipase. Displays antiallodynic and antihyperalgesic activity in an inflammatory pain model.

top caption :

Potent and selective FAAH inhibitor

extended description :

Potent and selective FAAH inhibitor

chemical name text :

Cyclohexylcarbamic acid 3 -(Aminocarbonyl)-[1,1 -biphenyl]-3-yl ester

formula :

C20H22N2O3

cas num :

546141-08-6

USD :

209 USD

product details :

Potent and selective FAAH inhibitor

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage