PBP 10 | Tocris Bioscience 4611 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PBP 10

catalog :

4611

quantity :

1 mg

price :

242 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Patel V, Zhabyeyev P, Chen X, Wang F, Paul M, Fan D, et al. PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease. Nat Commun. 2018;9:5390 pubmed publisher
Sanders J, Ashley B, Moon A, Woolley T, Swann K. PLCζ Induced Ca2+ Oscillations in Mouse Eggs Involve a Positive Feedback Cycle of Ca2+ Induced InsP3 Formation From Cytoplasmic PIP2. Front Cell Dev Biol. 2018;6:36 pubmed publisher
Courtin N, Fotso A, Fautrad P, Mas F, Alessi M, Riteau B. Antiviral activity of formyl peptide receptor 2 antagonists against influenza viruses. Antiviral Res. 2017;143:252-261 pubmed publisher

product information

brand :

Tocris

master code :

4611

SKU :

4611/1

product name :

PBP 10

description :

Selective FPR2 antagonist; cell permeable

target :

Formyl Peptide Receptor Antagonists

category :

Peptides

unit size :

1 mg

observed molecular weight :

1712.1

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

catalog number base :

4611

product keywords :

PBP10 Polyphosphoinositide-Binding Peptides FPR1 FPR2 formyl receptors FPRL1 inhibitors inhibits antagonists cell permeable antiviral influenza ERK Formyl Peptide Receptors Influenza Viruses 4611,

extended description :

Selective FPR2 antagonist; cell permeable

formula :

C 84 H 126 N 24 O 15

formula text :

C84H126N24O15

cas num :

794466-43-6

2020 USD :

234

2021 USD :

242 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage