BIIB 021 | Tocris Bioscience 4608 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIIB 021

catalog :

4608

quantity :

10 mg (also 50 mg)

price :

219 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4608

SKU :

4608/10

product name :

BIIB 021

description :

Selective Hsp90 inhibitor

target :

HSP90 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

main entrez gene id :

3320

purity :

98%

observed molecular weight :

318.76

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective, Hsp90 competitive inhibitor (Ki = 1.7 nM). Displays no significant activity at a range of ATP-binding kinases or Na+K+ ATPase. Induces degradation of HER-2 in vitro (EC50 = 38 nM in MCF-7 cells). Inhibits growth and promotes cell death in a variety of human tumor cells. Orally bioavailable.

catalog number base :

4608

product keywords :

BIIB021 heat shock proteins 90 hsp90 inhibitors chaperones HER-2 antitumor antitumour CNF2024 inhibits orally bioavailable potent selective CNF 2024 Hsp90 4608,

extended description :

Selective Hsp90 inhibitor

chemical name text :

6-Chloro-9-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-9H-purin-2-amine

formula :

C 14 H 15 ClN 6 O

formula text :

C14H15ClN6O

cas num :

848695-25-0

2020 USD :

214

2021 USD :

219 USD

alt names :

CNF 2024

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage