product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
LM 22A4
catalog :
4607
quantity :
25 mg
price :
389 USD
more info or order :
citations: 2
Reference
Garcia V, Rushton D, Tom C, Allen N, Kemp P, Svendsen C, et al. Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support. Front Neurosci. 2019;13:669 pubmed publisher
al Qudah M, Anderson C, Mahavadi S, Bradley Z, Akbarali H, Murthy K, et al. Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C. Am J Physiol Gastrointest Liver Physiol. 2014;306:G328-37 pubmed publisher
product information
brand :
Tocris
master code :
4607
SKU :
4607/25
product name :
LM 22A4
description :
Potent TrkB agonist
target :
Trk Receptor Agonists
category :
Small Molecules
unit size :
25 mg
purity :
98%
observed molecular weight :
339.34
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent tropomyosin-related kinase B (TrkB) agonist. Induces activation of Trk, Akt and ERK in mouse hippocampus and striatum and exhibits neurotrophic activity. Reverses deficits in motor task learning in mice following traumatic brain injury; restores respiratory function in a rat model of Rett syndrome.
catalog number base :
4607
product keywords :
LM22A4 tropomyosin related kinases B TrkB agonists potent Rett syndrome Trk Receptors 4607,
extended description :
Potent TrkB agonist
chemical name text :
N,N ,N Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
formula :
C 15 H 21 N 3 O 6
formula text :
C15H21N3O6
cas num :
37988-18-4
2020 USD :
374
2021 USD :
389 USD
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK