4607/5 | Tocris Bioscience 4607/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4607/5

catalog :

4607/5

quantity :

5 mg (also 25 mg)

price :

135 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Giacomoni J, Bruzelius A, Stamouli C, Rylander Ottosson D. Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons. Cells. 2020;9: pubmed publisher
Garcia V, Rushton D, Tom C, Allen N, Kemp P, Svendsen C, et al. Huntington's Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support. Front Neurosci. 2019;13:669 pubmed publisher
Drouin Ouellet J, Lau S, Brattås P, Rylander Ottosson D, Pircs K, Grassi D, et al. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways. EMBO Mol Med. 2017;9:1117-1131 pubmed publisher
al Qudah M, Anderson C, Mahavadi S, Bradley Z, Akbarali H, Murthy K, et al. Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C. Am J Physiol Gastrointest Liver Physiol. 2014;306:G328-37 pubmed publisher

image

image 1 :

Cat.No. 4607 - LM 22A4 C15H21N3O6 CAS No. 37988-18-4

product information

master code :

4607

SKU :

4607/5

product name :

LM 22A4

unit size :

5 mg (also 25 mg)

description :

Potent TrkB agonist

target :

Trk Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

339.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist. Induces activation of Trk, Akt and ERK in mouse hippocampus and striatum and exhibits neurotrophic activity. Reverses deficits in motor task learning in mice following traumatic brain injury; restores respiratory function in a rat model of Rett syndrome.

top caption :

Potent TrkB agonist

extended description :

Potent TrkB agonist

chemical name text :

N,N ,N Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide

formula :

C15H21N3O6

formula text :

C15H21N3O6

cas num :

37988-18-4

USD :

135 USD

product details :

Potent TrkB agonist

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage