PTIQ | Tocris Bioscience 4604 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PTIQ

catalog :

4604

quantity :

10 mg (also 50 mg)

price :

144 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4604

SKU :

4604/10

product name :

PTIQ

description :

Potent MMP-3 expression inhibitor; neuroprotective

target :

Additional MMP Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

235.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of MMP-3 expression (IC50 = 60 nM); down-regulates induction of MMP-3 in both stressed dopaminergic cells and activated microglia. Also suppresses proinflammatory responses and inhibits NO production in activated microglia. Attenuates motor deficits, prevents neurodegeneration and suppresses microglial activation in a Parkinson s disease mouse model. Brain penetrant.

catalog number base :

4604

product keywords :

potent MMP-3 expression inhibitors neuroprotective dopamingeric dopamine NO nitric oxide neurodegeneration Parkinson s disease blood brain barrier permeable MPTP - inhibits PD brain penetrant Matrix Metalloprotease Non-selective NOS 4604,

extended description :

Potent MMP-3 expression inhibitor; neuroprotective

chemical name text :

1-(3,4-Dihydro-7-hydroxy-6-methoxy-2(1H)-isoquinolinyl)-1-propanone

formula :

C 13 H 17 NO 3

formula text :

C13H17NO3

cas num :

1032822-42-6

2020 USD :

144

2021 USD :

144 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage