4603/10 | Tocris Bioscience 4603/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4603/10

catalog :

4603/10

quantity :

10 mg (also 50 mg)

price :

287 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Eddy M, Martin B, Wuthrich K. A2A Adenosine Receptor Partial Agonism Related to Structural Rearrangements in an Activation Microswitch. Structure. 2021;29:170-176.e3 pubmed publisher
Navarro G, Gonzalez A, Campanacci S, Rivas Santisteban R, Reyes Resina I, Casajuana Martin N, et al. Experimental and computational analysis of biased agonism on full-length and a C-terminally truncated adenosine A2A receptor. Comput Struct Biotechnol J. 2020;18:2723-2732 pubmed publisher

product information

master code :

4603

SKU :

4603/10

product name :

LUF 5834

unit size :

10 mg (also 50 mg)

description :

Potent adenosine A2A and A2B receptor partial agonist

target :

Adenosine A2a Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

348.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LUF 5834 is a potent A2A and A2B adenosine receptor partial agonist (Ki = 2.6 nM and EC50 = 12 nM respectively). Also exhibits selectivity for A1 over A3 (Ki values are 2.6 and 538 nM respectively).

top caption :

Potent adenosine A2A and A2B receptor partial agonist

extended description :

Potent adenosine A2A and A2B receptor partial agonist

chemical name text :

2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile

formula :

C17H12N6OS

cas num :

333962-91-7

USD :

287 USD

product details :

Potent adenosine A2A and A2B receptor partial agonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage