LDN 27219 | Tocris Bioscience 4602/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LDN 27219

catalog :

4602/10

quantity :

10 mg (also 50 mg)

price :

253 USD

citations: 2

Reference
Lee W, Al Ramahi I, Jeong H, Jang Y, Lin T, Adamski C, et al. Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1. J Clin Invest. 2022;132: pubmed publisher
Yeo S, Itahana Y, Guo A, Han R, Iwamoto K, Nguyen H, et al. Transglutaminase 2 contributes to a TP53-induced autophagy program to prevent oncogenic transformation. elife. 2016;5:e07101 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4602

SKU :

4602/10

product name :

LDN 27219

Description :

Transglutaminase 2 (TG2) inhibitor; reversible

target :

Additional Transferase Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

408.5

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LDN 27219 is a transglutaminase 2 (TG2) inhibitor (IC50 = 0.25 M). Binds at GTPase site; reversible.

extended description :

Transglutaminase 2 (TG2) inhibitor; reversible

chemical name text :

2-[(3,4-Dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]acetic acid hydrazide

formula :

C 20 H 16 N 4 O 2 S 2

formula text :

C20H16N4O2S2

cas num :

312946-37-5

USD :

253 USD

product details :

Transglutaminase 2 (TG2) inhibitor; reversible

storage :

Store at +4°C