4601/10 | Tocris Bioscience 4601/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4601/10

catalog :

4601/10

quantity :

10 mg (also 50 mg)

price :

251 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Su X, Liu Y, Shi M, Zhao Y, Liang X, Zhang L, et al. The GPR120 Agonist TUG-891 Inhibits the Motility and Phagocytosis of Mouse Alveolar Macrophages. Biomed Res Int. 2020;2020:1706168 pubmed publisher
Hilgendorf K, Johnson C, Mezger A, Rice S, Norris A, Demeter J, et al. Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019;179:1289-1305.e21 pubmed publisher
Inoue A, Raimondi F, Kadji F, Singh G, Kishi T, Uwamizu A, et al. Illuminating G-Protein-Coupling Selectivity of GPCRs. Cell. 2019;: pubmed publisher
Maillard V, Desmarchais A, Durcin M, Uzbekova S, Elis S. Docosahexaenoic acid (DHA) effects on proliferation and steroidogenesis of bovine granulosa cells. Reprod Biol Endocrinol. 2018;16:40 pubmed publisher
Gao B, Huang Q, Jie Q, Zhang H, Wang L, Guo Y, et al. Ginsenoside-Rb2 inhibits dexamethasone-induced apoptosis through promotion of GPR120 induction in bone marrow-derived mesenchymal stem cells. Stem Cells Dev. 2015;24:781-90 pubmed publisher

product information

master code :

4601

SKU :

4601/10

product name :

TUG 891

unit size :

10 mg (also 50 mg)

description :

Potent and selective FFA4 (GPR120) agonist

target :

Free Fatty Acid Receptor Agonists

category :

Small Molecules

purity :

99%

observed molecular weight :

364.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TUG 891 is a potent FFA4 (GPR120) agonist (pEC50 values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors (pEC50 = 4.19 for FFA1; displays no activity at FFA2 or FFA3). Cell permeable.

top caption :

Potent and selective FFA4 (GPR120) agonist

extended description :

Potent and selective FFA4 (GPR120) agonist

chemical name text :

4-[(4-Fluoro-4 -methyl[1,1 -biphenyl]-2-yl)methoxy]-benzenepropanoic acid

formula :

C23H21FO3

formula text :

C23H21FO3

cas num :

1374516-07-0

USD :

251 USD

product details :

Potent and selective FFA4 (GPR120) agonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage