Reference |
---|
Hung P, Hsu Y, Chen T, Ho C, Lin C. The Histone Demethylase Inhibitor GSK-J4 Is a Therapeutic Target for the Kidney Fibrosis of Diabetic Kidney Disease via DKK1 Modulation. Int J Mol Sci. 2022;23: pubmed publisher
|
Song Y, Hou G, Diep J, Ooi Y, Akopyants N, Beverley S, et al. Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation. Nucleic Acids Res. 2021;49:12706-12715 pubmed publisher
|
Lunazzi G, Buxade M, Riera Borrull M, Higuera L, Bonnin S, Huerga Encabo H, et al. NFAT5 Amplifies Antipathogen Responses by Enhancing Chromatin Accessibility, H3K27 Demethylation, and Transcription Factor Recruitment. J Immunol. 2021;206:2652-2667 pubmed publisher
|
Davis F, Tsoi L, Melvin W, denDekker A, Wasikowski R, Joshi A, et al. Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms. J Exp Med. 2021;218: pubmed publisher
|
Riching A, Danis E, Zhao Y, Cao Y, Chi C, Bagchi R, et al. Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis. J Mol Cell Cardiol. 2021;153:44-59 pubmed publisher
|
Browning L, Miller C, Kuczma M, Pietrzak M, Jing Y, Rempala G, et al. Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3+ Treg Cells. Cell Rep. 2020;33:108219 pubmed publisher
|
Davis F, denDekker A, Joshi A, Wolf S, Audu C, Melvin W, et al. Palmitate-TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing. Eur J Immunol. 2020;50:1929-1940 pubmed publisher
|
Nikolaev A, Fiveash J, Yang E. Combined Targeting of Mutant p53 and Jumonji Family Histone Demethylase Augments Therapeutic Efficacy of Radiation in H3K27M DIPG. Int J Mol Sci. 2020;21: pubmed publisher
|
Backe M, Jin C, Andreone L, Sankar A, Agger K, Helin K, et al. The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis. J Diabetes Res. 2019;2019:5451038 pubmed publisher
|
Lin C, Hsu Y, Huang Y, Shih Y, Wang C, Chiang W, et al. A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction. EMBO Mol Med. 2019;11: pubmed publisher
|
Bayo J, Tran T, Wang L, Peña Llopis S, Das A, Martinez E. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Rep. 2018;25:1040-1050.e5 pubmed publisher
|
Das A, Arifuzzaman S, Yoon T, Kim S, Chai J, Lee Y, et al. RNA sequencing reveals resistance of TLR4 ligand-activated microglial cells to inflammation mediated by the selective jumonji H3K27 demethylase inhibitor. Sci Rep. 2017;7:6554 pubmed publisher
|
Petruk S, Mariani S, De Dominici M, Porazzi P, Minieri V, Cai J, et al. Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification. Cell Rep. 2017;19:295-306 pubmed publisher
|
Ma K, Hung H, Svaren J. Epigenomic Regulation of Schwann Cell Reprogramming in Peripheral Nerve Injury. J Neurosci. 2016;36:9135-47 pubmed publisher
|
Sciacovelli M, Gonçalves E, Johnson T, Zecchini V, da Costa A, Gaude E, et al. Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition. Nature. 2016;537:544-547 pubmed publisher
|
Palomer E, Carretero J, Benvegnù S, Dotti C, Martin M. Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons. Nat Commun. 2016;7:11081 pubmed publisher
|
Pan D, Huang L, Zhu L, Zou T, Ou J, Zhou W, et al. Jmjd3-Mediated H3K27me3 Dynamics Orchestrate Brown Fat Development and Regulate White Fat Plasticity. Dev Cell. 2015;35:568-583 pubmed publisher
|
Kang S, Kim S, Chai J, Kim S, Won K, Lee Y, et al. Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation. PLoS ONE. 2015;10:e0135276 pubmed publisher
|
Aspuria P, Lunt S, Väremo L, Vergnes L, Gozo M, Beach J, et al. Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism. Cancer Metab. 2014;2:21 pubmed publisher
|
Perrigue P, Silva M, Warden C, Feng N, Reid M, Mota D, et al. The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines. Mol Cancer Res. 2015;13:636-50 pubmed publisher
|
Carey B, Finley L, Cross J, Allis C, Thompson C. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells. Nature. 2015;518:413-6 pubmed publisher
|
Gallagher K, Joshi A, Carson W, Schaller M, ALLEN R, Mukerjee S, et al. Epigenetic changes in bone marrow progenitor cells influence the inflammatory phenotype and alter wound healing in type 2 diabetes. Diabetes. 2015;64:1420-30 pubmed publisher
|
Petruk S, Black K, Kovermann S, Brock H, Mazo A. Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nat Commun. 2013;4:2841 pubmed publisher
|