Digoxin | Tocris Bioscience 4583 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Digoxin

catalog :

4583

quantity :

50 mg

price :

53 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Wang P, Wan W, Xiong S, Wang J, Zou D, Lan C, et al. HIF1α regulates glioma chemosensitivity through the transformation between differentiation and dedifferentiation in various oxygen levels. Sci Rep. 2017;7:7965 pubmed publisher
Wang P, Lan C, Xiong S, Zhao X, Shan Y, Hu R, et al. HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia. Oncotarget. 2017;8:28074-28092 pubmed publisher

product information

brand :

Tocris

master code :

4583

SKU :

4583/50

product name :

Digoxin

description :

Na+/K+ ATPase inhibitor

target :

Na+/K+ ATPase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

780.94

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibits membrane-bound -subunits of the Na+/K+ ATPase pump in myocytes. Increases RGS2 protein levels in primary vascular smooth muscle cells through an Na+/K+ ATPase pump-dependent mechanism. Also exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.17 M).

catalog number base :

4583

product keywords :

cardiac glycoside digitalis sodium potassium ATP Na+ K+ ATPase pump COVID-19 SARS-CoV-2 severe acute respiratory syndrome Na+/K+ ATPase COVID-19 Coronavirus 4583,

extended description :

Na+/K+ ATPase inhibitor

chemical name text :

4-[(3S,5R,8R,9S,10S,12R,13S,14S)-3-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-5-[(2S,4S,5R,6R)-4,5-Dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-4-hydroxy-6-methyl-oxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetra

formula :

C 41 H 64 O 14

formula text :

C41H64O14

cas num :

20830-75-5

2020 USD :

2021 USD :

53 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage