MLR 1023 | Tocris Bioscience 4582 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MLR 1023

catalog :

4582

quantity :

10 mg (also 50 mg)

price :

189 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, et al. Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy. Nat Commun. 2019;10:4262 pubmed publisher

product information

brand :

Tocris

master code :

4582

SKU :

4582/10

product name :

MLR 1023

description :

Selective allosteric activator of Lyn kinase

target :

Src Family Kinase Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

202.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective allosteric activator of Lyn kinase (EC50 = 63 nM); displays no significant activity against a range of 47 other kinases, including other Src family kinases such as Fyn, Lck and Src kinase. Reduces blood glucose levels without affecting in vivo insulin secretion. Orally bioavailable.

catalog number base :

4582

product keywords :

MLR1023 type II diabetes antidiabetic hyperglycemia lyn kinase inhibitors inhibits selective Src Kinases 4582,

extended description :

Selective allosteric activator of Lyn kinase

chemical name text :

5-(3-Methylphenoxy)-2(1H)-pyrimidinone

formula :

C 11 H 10 N 2 O 2

formula text :

C11H10N2O2

cas num :

41964-07-2

2020 USD :

183

2021 USD :

189 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage