4582/10 | Tocris Bioscience 4582/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4582/10

catalog :

4582/10

quantity :

10 mg (also 50 mg)

price :

238 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ferreira A, Casamento A, Carrillo Roas S, Halff E, Panambalana J, Subramaniam S, et al. Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis. Nat Commun. 2021;12:2424 pubmed publisher
Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, et al. Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy. Nat Commun. 2019;10:4262 pubmed publisher

product information

master code :

4582

SKU :

4582/10

product name :

MLR 1023

unit size :

10 mg (also 50 mg)

description :

Selective allosteric activator of Lyn kinase

target :

Src Family Kinase Activators

category :

Small Molecules

purity :

99%

observed molecular weight :

202.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MLR 1023 is a selective allosteric activator of Lyn kinase (EC50 = 63 nM); displays no significant activity against a range of 47 other kinases, including other Src family kinases such as Fyn, Lck and Src kinase. Reduces blood glucose levels without affecting in vivo insulin secretion. Orally bioavailable.

top caption :

Selective allosteric activator of Lyn kinase

extended description :

Selective allosteric activator of Lyn kinase

chemical name text :

5-(3-Methylphenoxy)-2(1H)-pyrimidinone

formula :

C11H10N2O2

formula text :

C11H10N2O2

cas num :

41964-07-2

USD :

238 USD

product details :

Selective allosteric activator of Lyn kinase

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage