NSC 687852 | Tocris Bioscience 4566 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NSC 687852

catalog :

4566

quantity :

10 mg (also 50 mg)

price :

149 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4566

SKU :

4566/10

product name :

NSC 687852

description :

Inhibitor of UCHL5 and USP14

target :

Deubiquitinating Enzyme Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

419.39

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of 19S regulatory particle associated deubiquitinating enzymes (DUBs), UCHL5 and USP14. Shows minimal inhibition of UCHL-1, UCHL-3, USP2, USP7, USP, BAP1 and proteasome activity. Induces apoptosis by cathepsin D-dependent caspase-cleavage (IC50 = 0.5 M). Displays antitumor activity in vivo .

catalog number base :

4566

product keywords :

NSC687852 19S regulatory particle associated deubiquitylating enzymes DUBs apoptosis UCHL5 USP14 cathepsin D dependent caspase cleavage antitumor b-AP15 Deubiquitinating Enzymes Apoptosis Inducers 4566,, DUB, Deubiquitinase

extended description :

Inhibitor of UCHL5 and USP14

chemical name text :

3,5-Bis[(4-nitrophenyl)methylene]-1-(1-oxo-2-propene-1-yl)-4-piperidone

formula :

C 22 H 17 N 3 O 6

formula text :

C22H17N3O6

cas num :

1009817-63-3

2020 USD :

149

2021 USD :

149 USD

alt names :

b-AP15

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage