ML 228 | Tocris Bioscience 4565 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ML 228

catalog :

4565

quantity :

10 mg (also 50 mg)

price :

242 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4565

SKU :

4565/10

product name :

ML 228

description :

HIF pathway activator

target :

HIF Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

415.49

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HIF pathway activator (EC50 values are 1.23 and 1.4 M for HRE gene reporter assay and HIF-1 nuclear translocation assay respectively); acts via chelation of iron, independently of PHD. Also exhibits 80% inhibition of the human A3 receptor, dopamine transporter, receptor, hERG and 5-HT2B receptor, and rat sodium channel site 2, at a concentration of 10 M.

catalog number base :

4565

product keywords :

ML228 hypoxia inducible factor HIF pathway activators iron chelators HRE Hypoxia Inducible Factors 4565, Hypoxia Inducible Factors, Hypoxia Inducible Factor

extended description :

HIF pathway activator

chemical name text :

N-([1,1 Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine

formula :

C 27 H 21 N 5

formula text :

C27H21N5

cas num :

1357171-62-0

2020 USD :

232

2021 USD :

242 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage