product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
HI TOPK 032
catalog :
4555
quantity :
10 mg
price :
168 USD
more info or order :
product information
brand :
Tocris
master code :
4555
SKU :
4555/10
product name :
HI TOPK 032
description :
Selective T-LAK-cell-originated protein kinase (TOPK) inhibitor
target :
Other MAPK Compounds
category :
Small Molecules
unit size :
10 mg
purity :
98%
observed molecular weight :
369.4
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
T-LAK-cell-originated protein kinase (TOPK) inhibitor; exhibits selectivity for TOPK over other MAPKK family members including ERK1, JNK1 and p38. Blocks proliferation of HCT116 colon cancer cells; suppresses tumor growth in a colon cancer xenograft model. Also inhibits Chk1 (IC50 = 9.6 M).
catalog number base :
4555
product keywords :
HITOPK032 TOPK T-LAK-cell-originated protein kinase MAPKK inhibitors inhibits selective antitumor colon cancer cells antiproliferatives Other MAPK 4555,
extended description :
Selective T-LAK-cell-originated protein kinase (TOPK) inhibitor
chemical name text :
N-(12-Cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide
formula :
C 20 H 11 N 5 OS
formula text :
C20H11N5OS
cas num :
487020-03-1
2020 USD :
168
2021 USD :
168 USD
storage :
Store at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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