Azilsartan | Tocris Bioscience 4553/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Azilsartan

catalog :

4553/10

quantity :

10 mg (also 50 mg)

price :

207 USD

product information

brand :

Tocris

master code :

4553

SKU :

4553/10

product name :

Azilsartan

description :

Potent AT1 inverse agonist; antihypertensive

target :

Angiotensin AT1 Receptor Inverse Agonists

category :

Small Molecules

unit sizes :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

456.45

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Azilsartan is a potent angiotensin II type 1 (AT1) receptor inverse agonist (IC50 = 2.6 nM at the human AT1 receptor). Inhibits angiotensin II-induced IP1 accumulation in COS-7 cells; decreases maximal contraction of rabbit aortic strips in a concentration-dependent manner (pD 2 = 9.9). Antihypertensive; prevents vascular cell proliferation and expression of PAI-1.

extended description :

Potent AT1 inverse agonist; antihypertensive

chemical name text :

2-Ethoxy-1-[[2 -(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid

formula :

C 25 H 20 N 4 O 5

formula text :

C25H20N4O5

cas num :

147403-03-0

USD :

207 USD

product details :

Potent AT1 inverse agonist; antihypertensive

storage :

Store at RT