IQ 3 | Tocris Bioscience 4550 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IQ 3

catalog :

4550

quantity :

10 mg (also 50 mg)

price :

140 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Easton C, Weir K, Scott A, Moen S, Barger Z, Folch A, et al. Genetic elimination of GABAergic neurotransmission reveals two distinct pacemakers for spontaneous waves of activity in the developing mouse cortex. J Neurosci. 2014;34:3854-63 pubmed publisher

product information

brand :

Tocris

master code :

4550

SKU :

4550/10

product name :

IQ 3

description :

Selective JNK3 inhibitor

target :

JNK/c-jun Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

341.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF- B/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 M). Also inhibits TNF- and IL-6 production in vitro .

catalog number base :

4550

product keywords :

IQ3 Selective JNK inhibitors inhibits JNK1 JNK2 JNK3 IQ3 JNK/c-jun c-jun MAPK kinases JNK/c-jun 4550,

extended description :

Selective JNK3 inhibitor

chemical name text :

11H-Indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime

formula :

C 20 H 11 N 3 O 3

cas num :

312538-03-7

2020 USD :

140

2021 USD :

140 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage