4536/10 | Tocris Bioscience 4536/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4536/10

catalog :

4536/10

quantity :

10 mg (also 50 mg)

price :

114 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Chan A, Kangas T, Qiu X, Uhlik M, Fulton R, Ottoson N, et al. Imprime PGG Enhances Anti-Tumor Effects of Tumor-Targeting, Anti-Angiogenic, and Immune Checkpoint Inhibitor Antibodies. Front Oncol. 2022;12:869078 pubmed publisher
Liu Y, Zeng Q, Deng C, Li M, Li L, Liu D, et al. Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine. Cell Discov. 2022;8:10 pubmed publisher
Derouazi M, Di Berardino Besson W, Belnoue E, Hoepner S, Walther R, Benkhoucha M, et al. Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell-Mediated Antitumor Immunity. Cancer Res. 2015;75:3020-31 pubmed publisher
Martins K, Steffens J, Van Tongeren S, Wells J, Bergeron A, Dickson S, et al. Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation. PLoS ONE. 2014;9:e89735 pubmed publisher

image

image 1 :

Cat.No. 4536 - Resiquimod C17H22N4O2 CAS No. 144875-48-9

product information

master code :

4536

SKU :

4536/10

product name :

Resiquimod

unit size :

10 mg (also 50 mg)

description :

Toll-like receptor 7 (TLR7) agonist

target :

Toll-like Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

314.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Resiquimod is a toll-like receptor 7 (TLR7) agonist. Induces upregulation of IL-6, IL-12, IFN- and iNOS expression in mouse bone marrow-derived macrophages (BMMs). Inhibits RANKL-induced osteoclast differentiation in mouse BMMs and human peripheral blood monocytes. Also promotes the differentiation of MDSCs into macrophages and dendritic cells. Proinflammatory and antiviral.

top caption :

Toll-like receptor 7 (TLR7) agonist

extended description :

Toll-like receptor 7 (TLR7) agonist

chemical name text :

1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol

formula :

C17H22N4O2

formula text :

C17H22N4O2

cas num :

144875-48-9

USD :

114 USD

product details :

Toll-like receptor 7 (TLR7) agonist

alt names :

R 848

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage