CZC 54252 hydrochloride | Tocris Bioscience 4534 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CZC 54252 hydrochloride

catalog :

4534

quantity :

10 mg (also 50 mg)

price :

216 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4534

SKU :

4534/10

product name :

CZC 54252 hydrochloride

description :

Potent LRRK2 inhibitor; neuroprotective

target :

LRRK2 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

541.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC50 values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). Attenuates neuronal injury induced by LRRK2-G2019S mutant activity in primary human neurons (EC50 = 1 nM).

catalog number base :

4534

product keywords :

CZC54252 leucine-rich repeat kinase 2 LRRK2 inhibitors inhibits potent neuroprotective neuronal injury parkinson s parkinsons LRRK2 4534, LRRK 2

extended description :

Potent LRRK2 inhibitor; neuroprotective

chemical name text :

N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride

formula :

C 22 H 25 ClN 6 O 4 S.HCl

formula text :

C22H25ClN6O4S.HCl

cas num :

1784253-05-9

2020 USD :

216

2021 USD :

216 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage