product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NCX 4040
catalog :
4531
quantity :
10 mg (also 50 mg)
price :
173 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
master code :
4531
SKU :
4531/10
product name :
NCX 4040
description :
NO-donating aspirin; anti-inflammatory and antitumor
target :
Cyclooxygenase Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
331.28
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
NO-donating aspirin; anti-inflammatory. Blocks inflammatory mediator production in isolated human monocytes (IC50 values are 0.07, 0.13, 0.15 and 0.18 M for IL-1 , PGE2, IL-10 and TNF- respectively). Decreases COX-2 expression (IC50 = 0.13 M); disrupts proteasome-mediated degradation of i B- . Antiproliferative in HCT116 colon cancer cells; sensitizes drug-resistant ovarian tumor cells to cisplatin (Cat. No. 2251).
catalog number base :
4531
product keywords :
NCX4040 NO nitric oxide donating donors aspirin para cyclooxygenase inhibitors inhibits anti-inflammatory inflammation NSAIDs antitumor cisplatin resistant Cyclooxygenase NO Donors/ Precursors 4531,
extended description :
NO-donating aspirin; anti-inflammatory and antitumor
chemical name text :
2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester
formula :
C 16 H 13 NO 7
formula text :
C16H13NO7
cas num :
287118-97-2
2020 USD :
173
2021 USD :
173 USD
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK