DIDS | Tocris Bioscience 4523 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

DIDS

catalog :

4523

quantity :

50 mg

price :

65 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Roebber J, Roper S, Chaudhari N. The role of the anion in salt (NaCl) detection by mouse taste buds. J Neurosci. 2019;: pubmed publisher
Cao Q, Zhao K, Zhong X, Zou Y, Yu H, Huang P, et al. SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viability. J Biol Chem. 2014;289:23189-99 pubmed publisher
Harper M, Poole A. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis. 2013;4:e969 pubmed publisher

product information

brand :

Tocris

master code :

4523

SKU :

4523/50

product name :

DIDS

description :

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

target :

Buffers, Chelators and Reagents

category :

Small Molecules

unit size :

50 mg

purity :

95%

observed molecular weight :

498.48

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ClC-Ka chloride channel blocker (IC50 = 100 M). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 M in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 M).

catalog number base :

4523

product keywords :

chloride channels ClC-Ka blockers trpm4 trpc4 transient receptor potential vanilloid receptors trpv1 rad51 homologous recombination dna damage repair double strand breaks 4,4-Diisothiocyanato-2,2-stilbenedisulfonic Other Chloride Channels 4523,

extended description :

Chloride channel blocker; TRPV1 modulator; RAD51 recombinase inhibitor

chemical name text :

4,4 -Diisothiocyanato-2,2 -stilbenedisulfonic acid disodium salt

formula :

C 16 H 8 N 2 Na 2 O 6 S 4

formula text :

C16H8N2Na2O6S4

cas num :

67483-13-0

2020 USD :

2021 USD :

65 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage