product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Cytarabine
catalog :
4520
quantity :
50 mg
price :
65 USD
more info or order :
citations: 2
Reference
Mathieson T, Franken H, Kosinski J, Kurzawa N, Zinn N, Sweetman G, et al. Systematic analysis of protein turnover in primary cells. Nat Commun. 2018;9:689 pubmed publisher
Bisikirska B, Bansal M, Shen Y, Teruya Feldstein J, Chaganti R, Califano A. Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression. Cancer Res. 2016;76:664-74 pubmed publisher
product information
brand :
Tocris
master code :
4520
SKU :
4520/50
product name :
Cytarabine
description :
Nucleoside analog; inhibits DNA replication
target :
DNA, RNA and Protein Synthesis Inhibitors
category :
Small Molecules
unit size :
50 mg
purity :
98%
observed molecular weight :
243.22
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Nucleoside analog of deoxycytidine; inhibits DNA replication by incorporating into DNA (IC50 = 0.04 M in L1210 and CEM cell lines). Displays no inhibitory effects on RNA synthesis. Causes S phase cell cycle arrest in ML-1 cell lines; cytotoxic in L5817Y leukemia cells. Antineoplastic and antileukemic agent.
catalog number base :
4520
product keywords :
Cytarabine supplier ara-C araC cytosine beta-D-arabinofuranoside arabinocytidine DNA replication inhibits nucleoside analog deoxycytidine incorporates synthesis anticancer antiproliferative antineoplastic antileukemic leukemia fragmentation antimetabolite Cytosine b-D-arabinofuranoside DNA, RNA and Protein Synthesis 4520,
extended description :
Nucleoside analog; inhibits DNA replication
chemical name text :
4-Amino-1- -D-arabinofuranosyl-2(1H)-pyrimidinone
formula :
C 9 H 13 N 3 O 5
formula text :
C9H13N3O5
cas num :
147-94-4
2020 USD :
62
2021 USD :
65 USD
alt names :
Cytosine b- D-arabinofuranoside
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK