4520/50 | Tocris Bioscience 4520/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4520/50

catalog :

4520/50

quantity :

50 mg

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Song S, Ashok A, Williams D, Kaufman M, Duff K, Sproul A. Efficient Derivation of Excitatory and Inhibitory Neurons from Human Pluripotent Stem Cells Stably Expressing Direct Reprogramming Factors. Curr Protoc. 2021;1:e141 pubmed publisher
Ye H, Minhajuddin M, Krug A, Pei S, Chou C, Culp Hill R, et al. The Hepatic Microenvironment Uniquely Protects Leukemia Cells through Induction of Growth and Survival Pathways Mediated by LIPG. Cancer Discov. 2021;11:500-519 pubmed publisher
Rothenburger T, McLaughlin K, Herold T, Schneider C, Oellerich T, Rothweiler F, et al. SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine. Commun Biol. 2020;3:324 pubmed publisher
Rodrigo R, Mendis N, Ibrahim M, Ma C, Kreinin E, Roma A, et al. Knockdown of BNIP3L or SQSTM1 alters cellular response to mitochondria target drugs. Autophagy. 2019;15:900-907 pubmed publisher
Mathieson T, Franken H, Kosinski J, Kurzawa N, Zinn N, Sweetman G, et al. Systematic analysis of protein turnover in primary cells. Nat Commun. 2018;9:689 pubmed publisher
Bisikirska B, Bansal M, Shen Y, Teruya Feldstein J, Chaganti R, Califano A. Elucidation and Pharmacological Targeting of Novel Molecular Drivers of Follicular Lymphoma Progression. Cancer Res. 2016;76:664-74 pubmed publisher

product information

master code :

4520

SKU :

4520/50

product name :

Cytarabine

unit size :

50 mg

description :

Nucleoside analog; inhibits DNA replication

target :

DNA, RNA and Protein Synthesis Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

243.22

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cytarabine is a nucleoside analog of deoxycytidine; inhibits DNA replication by incorporating into DNA (IC50 = 0.04 M in L1210 and CEM cell lines). Displays no inhibitory effects on RNA synthesis. Causes S phase cell cycle arrest in ML-1 cell lines; cytotoxic in L5817Y leukemia cells. Antineoplastic and antileukemic agent.

top caption :

Nucleoside analog; inhibits DNA replication

extended description :

Nucleoside analog; inhibits DNA replication

chemical name text :

4-Amino-1- -D-arabinofuranosyl-2(1H)-pyrimidinone

formula :

C9H13N3O5

formula text :

C9H13N3O5

cas num :

147-94-4

USD :

86 USD

product details :

Nucleoside analog; inhibits DNA replication

alt names :

Cytosine b- D -arabinofuranoside

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage