NS 2028 | Tocris Bioscience 4517 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 2028

catalog :

4517

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4517

SKU :

4517/10

product name :

NS 2028

description :

Potent soluble guanylyl cyclase (sGC) inhibitor

target :

Guanylyl Cyclase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

269.05

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). Blocks sGC activity in murine cerebellum induced by S-nitroso-glutathione and NMDA (IC50 values are 17 and 20 nM respectively). Inhibits VEGF-induced cGMP accumulation; abolishes VEGF-induced migration in postcapillary venular endothelial cells (CVEC).

catalog number base :

4517

product keywords :

NS2028 supplier soluble guanylyl cyclase sGC cGMP VEGF inhibitors inhibits potent antiproliferative Guanylyl Cyclase Other Nitric Oxide 4517,

extended description :

Potent soluble guanylyl cyclase (sGC) inhibitor

chemical name text :

8-Bromo-1H,4H-[1,2,4]oxadiazolo[3,4-c][1,4]benzoxazin-1-one

formula :

C 9 H 5 BrN 2 O 3

formula text :

C9H5BrN2O3

cas num :

204326-43-2

2020 USD :

205

2021 USD :

205 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage