TAME hydrochloride | Tocris Bioscience 4506 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAME hydrochloride

catalog :

4506

quantity :

50 mg

price :

45 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Coles G, Baglia L, Ackerman K. KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms. PLoS Genet. 2015;11:e1005525 pubmed publisher

product information

brand :

Tocris

master code :

4506

SKU :

4506/50

product name :

TAME hydrochloride

description :

Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

378.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Competitive inhibitor of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C); promotes Cdc20 autoubiquitination. Inhibits cyclin proteolysis in mitotic Xenopus oocyte extracts (IC50 = 12 M) and blocks cyclin degradation in interphase extract.

catalog number base :

4506

product keywords :

ubiquitin ligase anaphase-promoting complex/cyclosome APC inhibits inhibitors competitive mitotic arrest cyclin stabilization TAME hydrochloride HCl Ubiquitin E3 Ligases Mitosis 4506, E3 Ligase

extended description :

Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination

chemical name text :

N2-[(4-Methylphenyl)sulfonyl]-L-arginine methyl ester hydrochloride

formula :

C 14 H 22 N 4 O 4 S.HCl

formula text :

C14H22N4O4S.HCl

cas num :

1784-03-8

2020 USD :

2021 USD :

45 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage