This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
TAME hydrochloride
catalog :
4506/50
quantity :
50 mg
price :
45 USD
citations: 1
Reference
Coles G, Baglia L, Ackerman K. KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms. PLoS Genet. 2015;11:e1005525 pubmed publisher
product information
brand :
Tocris
SKU :
4506/50
product name :
TAME hydrochloride
unit sizes :
50 mg
description :
Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination
target :
Ubiquitin Ligase (E3) Inhibitors
category :
Small Molecules
purity :
99%
storage :
Store at -20°C
observed molecular weight :
378.87
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Competitive inhibitor of the ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C); promotes Cdc20 autoubiquitination. Inhibits cyclin proteolysis in mitotic Xenopus oocyte extracts (IC50 = 12 M) and blocks cyclin degradation in interphase extract.
catalog number base :
4506
extended description :
Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination
chemical name text :
N2-[(4-Methylphenyl)sulfonyl]-L-arginine methyl ester hydrochloride
formula :
C 14 H 22 N 4 O 4 S.HCl
formula text :
C14H22N4O4S.HCl
cas num :
1784-03-8
USD :
45 USD
default size :
TRUE
product details :
Ubiquitin ligase APC/C inhibitor; promotes Cdc20 autoubiquitination
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK