CC 0651 | Tocris Bioscience 4503 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CC 0651

catalog :

4503

quantity :

10 mg

price :

301 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rennekamp A, Huang X, Wang Y, Patel S, Lorello P, Cade L, et al. ?1 receptor ligands control a switch between passive and active threat responses. Nat Chem Biol. 2016;12:552-8 pubmed publisher

product information

brand :

Tocris

master code :

4503

SKU :

4503/10

product name :

CC 0651

description :

Allosteric inhibitor of hCdc34

target :

Ubiquitin Conjugating Enzyme (E2) Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

442.29

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Allosteric inhibitor of human Cdc34. Inhibits hCdc34-mediated ubiquitination of p27Kip1 (IC50 = 1.72 M). Exhibits selectivity for hCdc34 over Uba1, Ube2G1, UbcH7, UbcH5, Ube2N (Ubc13), Ube2R2, SMURF2, SspH1 and Rnf168.

catalog number base :

4503

product keywords :

CC0651 allosteric inhibitors inhibits hCDC34 ubiquitination selective ubl E2 conjugating enzymes Ubiquitin/Ubl E2 Conjugating Enzymes Post-translational Modifications 4503,

extended description :

Allosteric inhibitor of hCdc34

chemical name text :

(2R,3S,4S)-5-[4-(3,5-Dichlorophenyl)phenyl]-2,3-dihydroxy-4-(2-methoxyacetamido)pentanoic acid

formula :

C 20 H 21 Cl 2 NO 6

formula text :

C20H21Cl2NO6

cas num :

1319207-44-7

2020 USD :

295

2021 USD :

301 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage